Non-Opioid Pain Meds

Common medications: Acetaminophen (Tylenol), NSAIDs (Ibuprofen/Advil/Aleve/Naprosyn),
Gabapentin (Neurontin).

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How these medications help

  • Non-opioid pain medications are often the first step in treating pain and are commonly used along with opioids to improve comfort

  • They are most effective for mild to moderate pain and are often combined with other medications for more severe pain

  • Less pain means being able to be more active, sleep better, and have higher quality of life

  • These medications usually do not cause drowsiness like the opioids

  • They can be taken with opioids

How to take

  • Take it by mouth
  • All oral medications should be taken with fluids (not swallowed dry)

When will it work

  • Most non-opioid medications begin working within 30-60 minutes
  • It is important to take these medications if there is any pain, they should not be held because the "pain is not so bad"

Acetaminophen (Tylenol)

  • Do not take more than 3 gms per day, The hospice team will help determine the safest dosing and frequency

  • Remember that some opioid preparations (Vicodin, Norco) include Acetaminophen and this needs to be included in total daily dose

NSAIDs

  • Should be taken with food or after a meal

  • NSAIDs may not be safe for people with kidney problems, stomach ulcers, or a history of bleeding. Always check with your hospice team before using

Gabapentin (Neurontin)

  • Gabapentin is especially helpful for nerve pain, such as burning, tingling, or shooting pain

  • Dose range is wide, and higher doses may be used. Discuss with your hospice team

  • Often taken along with other pain medications

Common Side Effects

Tylenol - Very rare as long as stay within dose recommendations

NSAIDs - Upset stomach, kidney injury, increased risk of bleeding

Gabapentin - Drowsiness, constipation

When to Call Hospice

Nausea and vomiting

Pain is worsening or not relieved

Severe stomach pain develops

Vomiting or passing blood

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